Frequencies for first 10,000 rows of indi_pt variable in indi2017q2 dataset : 'Preferred Term'-level medical | terminology describing the Indication | for use | Freq. Percent Cum. ----------------------------------------+----------------------------------- 5q minus syndrome | 1 0.01 0.01 Abdominal discomfort | 17 0.17 0.18 Abdominal pain | 3 0.03 0.21 Abdominal pain lower | 2 0.02 0.23 Abdominal symptom | 1 0.01 0.24 Abnormal behaviour | 42 0.42 0.66 Abortion induced | 38 0.38 1.04 Acne | 4 0.04 1.08 Acne cystic | 3 0.03 1.11 Acral overgrowth | 2 0.02 1.13 Acromegaly | 22 0.22 1.35 Actinic keratosis | 1 0.01 1.36 Acute coronary syndrome | 3 0.03 1.39 Acute graft versus host disease | 1 0.01 1.40 Acute kidney injury | 1 0.01 1.41 Acute lymphocytic leukaemia | 28 0.28 1.69 Acute myeloid leukaemia | 11 0.11 1.80 Acute myocardial infarction | 1 0.01 1.81 Adenocarcinoma pancreas | 2 0.02 1.83 Adjuvant therapy | 2 0.02 1.85 Adverse event | 17 0.17 2.02 Affective disorder | 22 0.22 2.24 Age-related macular degeneration | 3 0.03 2.27 Aggression | 21 0.21 2.48 Agitation | 10 0.10 2.58 Alanine aminotransferase increased | 1 0.01 2.59 Alcoholism | 1 0.01 2.60 Allergy prophylaxis | 3 0.03 2.63 Alopecia | 38 0.38 3.01 Amyloidosis | 5 0.05 3.06 Anaemia | 20 0.20 3.26 Anaemia of malignant disease | 5 0.05 3.31 Anaemia prophylaxis | 2 0.02 3.33 Anaesthesia | 1 0.01 3.34 Analgesic intervention supportive the.. | 1 0.01 3.35 Analgesic therapy | 13 0.13 3.48 Androgen replacement therapy | 1 0.01 3.49 Androgenetic alopecia | 20 0.20 3.69 Anger | 12 0.12 3.81 Angina pectoris | 3 0.03 3.84 Angiodysplasia | 1 0.01 3.85 Ankylosing spondylitis | 15 0.15 4.00 Anti-infective therapy | 3 0.03 4.03 Antiallergic therapy | 1 0.01 4.04 Antibiotic prophylaxis | 4 0.04 4.08 Antibiotic therapy | 3 0.03 4.11 Anticoagulant therapy | 20 0.20 4.31 Antidepressant therapy | 8 0.08 4.39 Antifungal prophylaxis | 9 0.09 4.48 Antiinflammatory therapy | 4 0.04 4.52 Antiphospholipid syndrome | 4 0.04 4.56 Antiplatelet therapy | 6 0.06 4.62 Antiretroviral therapy | 2 0.02 4.64 Antiviral prophylaxis | 10 0.10 4.74 Antiviral treatment | 4 0.04 4.78 Anuria | 3 0.03 4.81 Anxiety | 103 1.03 5.84 Anxiety disorder | 5 0.05 5.89 Anxiolytic therapy | 4 0.04 5.93 Appendicectomy | 3 0.03 5.96 Arrhythmia | 7 0.07 6.03 Arrhythmogenic right ventricular dysp.. | 2 0.02 6.05 Arterial disorder | 1 0.01 6.06 Arterial occlusive disease | 1 0.01 6.07 Arthralgia | 27 0.27 6.34 Arthritis | 25 0.25 6.59 Arthritis reactive | 1 0.01 6.60 Arthropathy | 3 0.03 6.63 Artificial menopause | 1 0.01 6.64 Ascites | 1 0.01 6.65 Aspartate aminotransferase increased | 1 0.01 6.66 Aspergillus infection | 1 0.01 6.67 Asthenia | 3 0.03 6.70 Asthma | 112 1.12 7.82 Astrocytoma, low grade | 1 0.01 7.83 Asymptomatic HIV infection | 2 0.02 7.85 Atrial fibrillation | 75 0.75 8.60 Atrial septal defect | 6 0.06 8.66 Atrial tachycardia | 2 0.02 8.68 Attention deficit/hyperactivity disor.. | 205 2.05 10.73 Atypical mycobacterial infection | 1 0.01 10.74 Autism spectrum disorder | 27 0.27 11.01 Autoimmune hepatitis | 1 0.01 11.02 Autoimmune thyroiditis | 1 0.01 11.03 Autonomic failure syndrome | 1 0.01 11.04 Autonomic neuropathy | 1 0.01 11.05 B-cell lymphoma | 49 0.49 11.54 Back disorder | 4 0.04 11.58 Back pain | 22 0.22 11.80 Bacteraemia | 1 0.01 11.81 Bacterial infection | 2 0.02 11.83 Basal cell carcinoma | 1 0.01 11.84 Basedow's disease | 1 0.01 11.85 Benign prostatic hyperplasia | 13 0.13 11.98 Bile duct adenocarcinoma | 1 0.01 11.99 Binge eating | 1 0.01 12.00 Bipolar I disorder | 10 0.10 12.10 Bipolar II disorder | 2 0.02 12.12 Bipolar disorder | 197 1.97 14.09 Bladder cancer | 3 0.03 14.12 Bladder disorder | 2 0.02 14.14 Blood albumin decreased | 1 0.01 14.15 Blood calcium decreased | 1 0.01 14.16 Blood calcium increased | 1 0.01 14.17 Blood cholesterol | 16 0.16 14.33 Blood cholesterol abnormal | 26 0.26 14.59 Blood cholesterol increased | 39 0.39 14.98 Blood glucose abnormal | 1 0.01 14.99 Blood glucose increased | 2 0.02 15.01 Blood iron decreased | 1 0.01 15.02 Blood lead | 3 0.03 15.05 Blood magnesium decreased | 1 0.01 15.06 Blood potassium abnormal | 1 0.01 15.07 Blood potassium decreased | 1 0.01 15.08 Blood pressure abnormal | 50 0.50 15.58 Blood pressure decreased | 1 0.01 15.59 Blood pressure increased | 3 0.03 15.62 Blood pressure measurement | 19 0.19 15.81 Blood test abnormal | 1 0.01 15.82 Blood testosterone decreased | 1 0.01 15.83 Blood triglycerides | 2 0.02 15.85 Blood triglycerides abnormal | 1 0.01 15.86 Blood triglycerides increased | 5 0.05 15.91 Blood uric acid increased | 1 0.01 15.92 Body height below normal | 2 0.02 15.94 Body temperature increased | 1 0.01 15.95 Bone density abnormal | 2 0.02 15.97 Bone density decreased | 2 0.02 15.99 Bone disorder | 11 0.11 16.10 Bone giant cell tumour | 2 0.02 16.12 Bone marrow conditioning regimen | 11 0.11 16.23 Bone pain | 7 0.07 16.30 Bowel movement irregularity | 1 0.01 16.31 Bradycardia | 1 0.01 16.32 Bradyphrenia | 1 0.01 16.33 Brain neoplasm | 1 0.01 16.34 Brain stem glioma | 1 0.01 16.35 Breakthrough pain | 2 0.02 16.37 Breast cancer | 73 0.73 17.10 Breast cancer female | 5 0.05 17.15 Breast cancer metastatic | 30 0.30 17.45 Breast cancer stage II | 2 0.02 17.47 Breast cancer stage III | 4 0.04 17.51 Breast cancer stage IV | 1 0.01 17.52 Bronchitis | 10 0.10 17.62 Bronchitis chronic | 8 0.08 17.70 Bronchopulmonary aspergillosis | 2 0.02 17.72 Burkitt's lymphoma | 8 0.08 17.80 Burning sensation | 7 0.07 17.87 C-reactive protein increased | 2 0.02 17.89 Calcium deficiency | 1 0.01 17.90 Cancer pain | 6 0.06 17.96 Candida infection | 1 0.01 17.97 Carcinoid syndrome | 3 0.03 18.00 Carcinoid tumour | 7 0.07 18.07 Cardiac disorder | 47 0.47 18.54 Cardiac failure | 28 0.28 18.82 Cardiac failure acute | 13 0.13 18.95 Cardiac failure chronic | 2 0.02 18.97 Cardiac failure congestive | 10 0.10 19.07 Cardiovascular disorder | 15 0.15 19.22 Cardiovascular event prophylaxis | 36 0.36 19.58 Cellulitis | 9 0.09 19.67 Central nervous system lymphoma | 1 0.01 19.68 Cerebral haemorrhage | 10 0.10 19.78 Cerebral infarction | 2 0.02 19.80 Cerebral oedema management | 1 0.01 19.81 Cerebral toxoplasmosis | 1 0.01 19.82 Cerebrovascular accident prophylaxis | 18 0.18 20.00 Cervical spinal stenosis | 1 0.01 20.01 Chelation therapy | 2 0.02 20.03 Chemotherapy | 24 0.24 20.27 Chest discomfort | 1 0.01 20.28 Chest pain | 7 0.07 20.35 Chills | 2 0.02 20.37 Chloasma | 2 0.02 20.39 Cholecystectomy | 1 0.01 20.40 Cholecystitis | 5 0.05 20.45 Choroidal neovascularisation | 1 0.01 20.46 Choroiditis | 1 0.01 20.47 Chronic fatigue syndrome | 2 0.02 20.49 Chronic gastritis | 4 0.04 20.53 Chronic hepatitis B | 1 0.01 20.54 Chronic hepatitis C | 5 0.05 20.59 Chronic kidney disease | 6 0.06 20.65 Chronic lymphocytic leukaemia | 42 0.42 21.07 Chronic myeloid leukaemia | 32 0.32 21.39 Chronic myelomonocytic leukaemia | 3 0.03 21.42 Chronic obstructive pulmonary disease | 35 0.35 21.77 Chronic spontaneous urticaria | 1 0.01 21.78 Circadian rhythm sleep disorder | 1 0.01 21.79 Coagulopathy | 3 0.03 21.82 Colitis | 2 0.02 21.84 Colitis ulcerative | 15 0.15 21.99 Colon cancer | 8 0.08 22.07 Colorectal adenocarcinoma | 2 0.02 22.09 Colorectal cancer | 31 0.31 22.40 Colorectal cancer metastatic | 50 0.50 22.90 Complex regional pain syndrome | 1 0.01 22.91 Conduct disorder | 1 0.01 22.92 Confusional state | 1 0.01 22.93 Conjunctival oedema | 2 0.02 22.95 Conjunctivitis | 1 0.01 22.96 Conjunctivitis allergic | 1 0.01 22.97 Connective tissue disorder | 1 0.01 22.98 Constipation | 38 0.38 23.36 Constipation prophylaxis | 3 0.03 23.39 Contraception | 25 0.25 23.64 Cor pulmonale chronic | 1 0.01 23.65 Cord blood transplant therapy | 3 0.03 23.68 Corneal dystrophy | 1 0.01 23.69 Coronary arterial stent insertion | 1 0.01 23.70 Coronary artery bypass | 6 0.06 23.76 Coronary artery disease | 12 0.12 23.88 Coronary artery insufficiency | 1 0.01 23.89 Coronary artery occlusion | 1 0.01 23.90 Coronary artery thrombosis | 1 0.01 23.91 Cough | 7 0.07 23.98 Crohn's disease | 63 0.63 24.61 Cystic fibrosis | 5 0.05 24.66 Cystic fibrosis lung | 3 0.03 24.69 Cystitis | 2 0.02 24.71 Cytomegalovirus infection | 2 0.02 24.73 Decreased appetite | 1 0.01 24.74 Deep vein thrombosis | 6 0.06 24.80 Defiant behaviour | 2 0.02 24.82 Dehydration | 2 0.02 24.84 Delirium | 3 0.03 24.87 Delusion | 3 0.03 24.90 Delusional disorder, unspecified type | 5 0.05 24.95 Dementia | 1 0.01 24.96 Dementia Alzheimer's type | 1 0.01 24.97 Depressed mood | 1 0.01 24.98 Depression | 172 1.72 26.70 Dermatitis | 4 0.04 26.74 Dermatitis contact | 1 0.01 26.75 Diabetes mellitus | 105 1.05 27.80 Diabetes mellitus management | 2 0.02 27.82 Diabetic neuropathy | 8 0.08 27.90 Diabetic retinal oedema | 2 0.02 27.92 Dialysis | 1 0.01 27.93 Diarrhoea | 18 0.18 28.11 Diffuse large B-cell lymphoma | 33 0.33 28.44 Diffuse panbronchiolitis | 1 0.01 28.45 Diplopia | 1 0.01 28.46 Discomfort | 1 0.01 28.47 Disruptive mood dysregulation disorder | 1 0.01 28.48 Dissociative identity disorder | 1 0.01 28.49 Disturbance in attention | 2 0.02 28.51 Diuretic therapy | 10 0.10 28.61 Diverticulitis | 1 0.01 28.62 Dizziness | 2 0.02 28.64 Drug therapy | 19 0.19 28.83 Drug use disorder | 17 0.17 29.00 Dry age-related macular degeneration | 1 0.01 29.01 Dry eye | 2 0.02 29.03 Dry mouth | 1 0.01 29.04 Dry skin | 2 0.02 29.06 Dumping syndrome | 1 0.01 29.07 Duodenitis | 3 0.03 29.10 Dust allergy | 1 0.01 29.11 Dyslexia | 1 0.01 29.12 Dyslipidaemia | 12 0.12 29.24 Dysmenorrhoea | 1 0.01 29.25 Dyspepsia | 26 0.26 29.51 Dyspnoea | 7 0.07 29.58 Dysuria | 1 0.01 29.59 Ear pain | 1 0.01 29.60 Eczema | 2 0.02 29.62 Electrolyte substitution therapy | 1 0.01 29.63 Embolism | 2 0.02 29.65 Emotional disorder | 4 0.04 29.69 Emphysema | 8 0.08 29.77 Encephalopathy | 1 0.01 29.78 Endometrial cancer | 2 0.02 29.80 Endometriosis | 2 0.02 29.82 Endoscopy gastrointestinal | 3 0.03 29.85 Enteral nutrition | 1 0.01 29.86 Epilepsy | 20 0.20 30.06 Epstein-Barr viraemia | 2 0.02 30.08 Erectile dysfunction | 2 0.02 30.10 Erysipelas | 2 0.02 30.12 Erythema | 1 0.01 30.13 Erythrodermic psoriasis | 2 0.02 30.15 Escherichia test positive | 1 0.01 30.16 Essential hypertension | 2 0.02 30.18 Evans syndrome | 1 0.01 30.19 Exposure to communicable disease | 2 0.02 30.21 Eye disorder | 4 0.04 30.25 Eye infection staphylococcal | 1 0.01 30.26 Eye inflammation | 1 0.01 30.27 Fabry's disease | 5 0.05 30.32 Factor IX deficiency | 3 0.03 30.35 Factor VIII deficiency | 2 0.02 30.37 Faeces hard | 3 0.03 30.40 Fall | 1 0.01 30.41 Fatigue | 4 0.04 30.45 Febrile neutropenia | 2 0.02 30.47 Feeding disorder | 4 0.04 30.51 Feeling of relaxation | 1 0.01 30.52 Fibromyalgia | 30 0.30 30.82 Fibrous dysplasia of bone | 1 0.01 30.83 Fluid imbalance | 1 0.01 30.84 Fluid retention | 5 0.05 30.89 Focal dyscognitive seizures | 1 0.01 30.90 Foetal exposure during pregnancy | 5 0.05 30.95 Foetal growth restriction | 1 0.01 30.96 Folate deficiency | 1 0.01 30.97 Folliculitis | 1 0.01 30.98 Fungal infection | 7 0.07 31.05 Furuncle | 3 0.03 31.08 Gait disturbance | 8 0.08 31.16 Gastric cancer | 7 0.07 31.23 Gastric disorder | 7 0.07 31.30 Gastric pH decreased | 1 0.01 31.31 Gastric ulcer | 2 0.02 31.33 Gastric ulcer helicobacter | 1 0.01 31.34 Gastritis | 10 0.10 31.44 Gastritis erosive | 2 0.02 31.46 Gastritis prophylaxis | 5 0.05 31.51 Gastroenteritis | 2 0.02 31.53 Gastrointestinal disorder | 3 0.03 31.56 Gastrointestinal disorder therapy | 1 0.01 31.57 Gastrointestinal haemorrhage | 6 0.06 31.63 Gastrointestinal stromal tumour | 3 0.03 31.66 Gastrooesophageal reflux disease | 88 0.88 32.54 Gastrooesophageal reflux prophylaxis | 1 0.01 32.55 Gaucher's disease | 1 0.01 32.56 General physical condition | 1 0.01 32.57 General physical health deterioration | 4 0.04 32.61 Generalised anxiety disorder | 1 0.01 32.62 Generalised tonic-clonic seizure | 1 0.01 32.63 Genital candidiasis | 1 0.01 32.64 Genital neoplasm malignant female | 6 0.06 32.70 Gestational diabetes | 2 0.02 32.72 Gigantism | 1 0.01 32.73 Glaucoma | 20 0.20 32.93 Glioblastoma | 4 0.04 32.97 Glioblastoma multiforme | 5 0.05 33.02 Glycogen storage disease type II | 1 0.01 33.03 Gout | 5 0.05 33.08 Gouty arthritis | 2 0.02 33.10 Graft versus host disease | 9 0.09 33.19 Granulocytopenia | 1 0.01 33.20 Granuloma annulare | 1 0.01 33.21 Granulomatosis with polyangiitis | 2 0.02 33.23 Growth failure | 1 0.01 33.24 Growth hormone deficiency | 6 0.06 33.30 Growth hormone-producing pituitary tu.. | 1 0.01 33.31 Growth of eyelashes | 2 0.02 33.33 Guttate psoriasis | 1 0.01 33.34 HER-2 positive breast cancer | 16 0.16 33.50 HER-2 positive gastric cancer | 1 0.01 33.51 HIV infection | 113 1.13 34.64 Haematochezia | 1 0.01 34.65 Haemoglobin decreased | 1 0.01 34.66 Haemolytic uraemic syndrome | 18 0.18 34.84 Haemoptysis | 2 0.02 34.86 Haemorrhage | 2 0.02 34.88 Haemorrhoids | 6 0.06 34.94 Haemosiderosis | 1 0.01 34.95 Haemostasis | 1 0.01 34.96 Hair disorder | 2 0.02 34.98 Hallucination, auditory | 2 0.02 35.00 Headache | 16 0.16 35.16 Heart disease congenital | 1 0.01 35.17 Heart rate | 1 0.01 35.18 Heart rate abnormal | 3 0.03 35.21 Heart transplant | 26 0.26 35.47 Helicobacter infection | 12 0.12 35.59 Hepatic failure | 2 0.02 35.61 Hepatic function abnormal | 1 0.01 35.62 Hepatitis C | 18 0.18 35.80 Hepatitis alcoholic | 1 0.01 35.81 Hepatocellular carcinoma | 5 0.05 35.86 Hereditary angioedema | 5 0.05 35.91 Hereditary haemochromatosis | 1 0.01 35.92 Hereditary haemorrhagic telangiectasia | 1 0.01 35.93 Hernia hiatus repair | 1 0.01 35.94 Herpes virus infection | 1 0.01 35.95 Herpes zoster | 3 0.03 35.98 Herpes zoster oticus | 5 0.05 36.03 Hiatus hernia | 7 0.07 36.10 Hip arthroplasty | 2 0.02 36.12 Hirsutism | 1 0.01 36.13 Hormone replacement therapy | 5 0.05 36.18 Hormone therapy | 2 0.02 36.20 Hormone-refractory prostate cancer | 4 0.04 36.24 Hot flush | 1 0.01 36.25 Huntington's disease | 2 0.02 36.27 Hyperammonaemia | 2 0.02 36.29 Hypercalcaemia | 1 0.01 36.30 Hyperchlorhydria | 1 0.01 36.31 Hypercholesterolaemia | 22 0.22 36.53 Hyperglycaemia | 1 0.01 36.54 Hyperkalaemia | 1 0.01 36.55 Hyperlipidaemia | 22 0.22 36.77 Hyperprolactinaemia | 1 0.01 36.78 Hypersensitivity | 31 0.31 37.09 Hypertension | 271 2.71 39.80 Hypertonic bladder | 5 0.05 39.85 Hyperuricaemia | 13 0.13 39.98 Hypoaesthesia | 1 0.01 39.99 Hypoalbuminaemia | 1 0.01 40.00 Hypocalcaemia | 3 0.03 40.03 Hypogammaglobulinaemia | 2 0.02 40.05 Hypoglycaemia | 1 0.01 40.06 Hypokalaemia | 7 0.07 40.13 Hypolipidaemia | 1 0.01 40.14 Hyponatraemia | 13 0.13 40.27 Hypopharyngeal cancer | 5 0.05 40.32 Hypophosphataemia | 2 0.02 40.34 Hypopituitarism | 2 0.02 40.36 Hypotension | 3 0.03 40.39 Hypothyroidism | 45 0.45 40.84 Hypotrichosis | 1 0.01 40.85 Hypoxia | 1 0.01 40.86 Hysterectomy | 3 0.03 40.89 Idiopathic urticaria | 1 0.01 40.90 Ill-defined disorder | 2 0.02 40.92 Immune system disorder | 1 0.01 40.93 Immune thrombocytopenic purpura | 2 0.02 40.95 Immune tolerance induction | 2 0.02 40.97 Immunosuppressant drug therapy | 4 0.04 41.01 Immunosuppression | 5 0.05 41.06 Impulse-control disorder | 3 0.03 41.09 Inappropriate antidiuretic hormone se.. | 1 0.01 41.10 Incontinence | 1 0.01 41.11 Induction of cervix ripening | 1 0.01 41.12 Infantile spasms | 1 0.01 41.13 Infection | 21 0.21 41.34 Infection prophylaxis | 14 0.14 41.48 Infertility | 2 0.02 41.50 Inflammation | 2 0.02 41.52 Inflammatory bowel disease | 3 0.03 41.55 Influenza | 3 0.03 41.58 Influenza immunisation | 6 0.06 41.64 Infusion related reaction | 1 0.01 41.65 Injection site anaesthesia | 1 0.01 41.66 Insomnia | 50 0.50 42.16 Insulin-requiring type 2 diabetes mel.. | 1 0.01 42.17 Intellectual disability | 1 0.01 42.18 Intercostal neuralgia | 1 0.01 42.19 Intermittent claudication | 1 0.01 42.20 International normalised ratio | 1 0.01 42.21 Interstitial lung disease | 1 0.01 42.22 Intervertebral disc compression | 1 0.01 42.23 Intervertebral disc protrusion | 3 0.03 42.26 Intestinal resection | 1 0.01 42.27 Intraocular pressure increased | 3 0.03 42.30 Intraocular pressure test abnormal | 1 0.01 42.31 Invasive ductal breast carcinoma | 5 0.05 42.36 Iron deficiency | 2 0.02 42.38 Iron deficiency anaemia | 2 0.02 42.40 Iron overload | 1 0.01 42.41 Irritable bowel syndrome | 5 0.05 42.46 Ischaemic cardiomyopathy | 2 0.02 42.48 Ischaemic heart disease prophylaxis | 5 0.05 42.53 Ischaemic stroke | 2 0.02 42.55 Joint swelling | 1 0.01 42.56 Juvenile Paget's disease | 1 0.01 42.57 Juvenile idiopathic arthritis | 6 0.06 42.63 Knee arthroplasty | 1 0.01 42.64 Labour induction | 1 0.01 42.65 Labyrinthitis | 1 0.01 42.66 Laxative supportive care | 1 0.01 42.67 Left ventricular dysfunction | 3 0.03 42.70 Leukopenia | 3 0.03 42.73 Lipids increased | 7 0.07 42.80 Liver disorder | 2 0.02 42.82 Liver transplant | 11 0.11 42.93 Local anaesthesia | 3 0.03 42.96 Low density lipoprotein | 2 0.02 42.98 Low density lipoprotein increased | 7 0.07 43.05 Lower respiratory tract infection | 1 0.01 43.06 Lower urinary tract symptoms | 1 0.01 43.07 Lung cancer metastatic | 1 0.01 43.08 Lung disorder | 3 0.03 43.11 Lung infection | 1 0.01 43.12 Lung infiltration | 2 0.02 43.14 Lung neoplasm malignant | 8 0.08 43.22 Lung transplant | 1 0.01 43.23 Lupus nephritis | 10 0.10 43.33 Lymphangioleiomyomatosis | 4 0.04 43.37 Lymphocytic leukaemia | 4 0.04 43.41 Lymphoma | 8 0.08 43.49 Macular degeneration | 2 0.02 43.51 Major depression | 8 0.08 43.59 Malaria prophylaxis | 1 0.01 43.60 Malignant lymphoid neoplasm | 9 0.09 43.69 Malignant melanoma | 10 0.10 43.79 Malnutrition | 3 0.03 43.82 Mania | 2 0.02 43.84 Mantle cell lymphoma | 42 0.42 44.26 Maternal exposure timing unspecified | 2 0.02 44.28 Meningioma malignant | 1 0.01 44.29 Menopause | 3 0.03 44.32 Menstrual cycle management | 1 0.01 44.33 Menstrual discomfort | 1 0.01 44.34 Menstrual disorder | 1 0.01 44.35 Mental disorder | 13 0.13 44.48 Metastases to bone | 6 0.06 44.54 Metastases to central nervous system | 1 0.01 44.55 Metastatic gastric cancer | 20 0.20 44.75 Metastatic malignant melanoma | 4 0.04 44.79 Metastatic renal cell carcinoma | 7 0.07 44.86 Migraine | 36 0.36 45.22 Migraine prophylaxis | 2 0.02 45.24 Mineral supplementation | 7 0.07 45.31 Mood altered | 2 0.02 45.33 Mood swings | 17 0.17 45.50 Mouth haemorrhage | 2 0.02 45.52 Mouth ulceration | 1 0.01 45.53 Mucopolysaccharidosis I | 2 0.02 45.55 Mucopolysaccharidosis II | 2 0.02 45.57 Mucopolysaccharidosis VI | 2 0.02 45.59 Mucosal inflammation | 1 0.01 45.60 Multiple allergies | 9 0.09 45.69 Multiple sclerosis | 146 1.46 47.15 Multiple sclerosis relapse | 3 0.03 47.18 Muscle contractions involuntary | 1 0.01 47.19 Muscle disorder | 3 0.03 47.22 Muscle relaxant therapy | 8 0.08 47.30 Muscle spasms | 17 0.17 47.47 Muscle spasticity | 1 0.01 47.48 Musculoskeletal discomfort | 2 0.02 47.50 Musculoskeletal pain | 1 0.01 47.51 Musculoskeletal stiffness | 2 0.02 47.53 Myalgia | 3 0.03 47.56 Myasthenia gravis | 1 0.01 47.57 Mycobacterium avium complex infection | 3 0.03 47.60 Myelodysplastic syndrome | 9 0.09 47.69 Myelofibrosis | 9 0.09 47.78 Myeloproliferative neoplasm | 1 0.01 47.79 Myocardial infarction | 12 0.12 47.91 Myocardial ischaemia | 4 0.04 47.95 Myoclonus | 1 0.01 47.96 Narcolepsy | 1 0.01 47.97 Nasal congestion | 2 0.02 47.99 Nasal dryness | 1 0.01 48.00 Nasopharyngeal cancer | 1 0.01 48.01 Nausea | 49 0.49 48.50 Neck injury | 1 0.01 48.51 Neck pain | 4 0.04 48.55 Neoplasm | 5 0.05 48.60 Neoplasm malignant | 17 0.17 48.77 Neovascular age-related macular degen.. | 9 0.09 48.86 Nephrogenic anaemia | 14 0.14 49.00 Nephropathy | 1 0.01 49.01 Nephrotic syndrome | 1 0.01 49.02 Nerve compression | 1 0.01 49.03 Nerve injury | 6 0.06 49.09 Nervous system disorder | 1 0.01 49.10 Nervousness | 5 0.05 49.15 Neuralgia | 14 0.14 49.29 Neuroendocrine tumour | 13 0.13 49.42 Neuropathy peripheral | 28 0.28 49.70 Neurosarcoidosis | 2 0.02 49.72 Neutropenia | 2 0.02 49.74 Neutrophil count decreased | 1 0.01 49.75 Niemann-Pick disease | 3 0.03 49.78 Night sweats | 1 0.01 49.79 Nightmare | 2 0.02 49.81 Nodal marginal zone B-cell lymphoma | 9 0.09 49.90 Non-Hodgkin's lymphoma | 50 0.50 50.40 Non-Hodgkin's lymphoma unspecified hi.. | 5 0.05 50.45 Non-small cell lung cancer | 43 0.43 50.88 Nutritional supplementation | 1 0.01 50.89 Obsessive-compulsive disorder | 10 0.10 50.99 Oedema | 6 0.06 51.05 Oedema due to cardiac disease | 1 0.01 51.06 Oedema due to hepatic disease | 1 0.01 51.07 Oedema due to renal disease | 1 0.01 51.08 Oedema peripheral | 2 0.02 51.10 Oesophageal candidiasis | 4 0.04 51.14 Oesophageal disorder | 2 0.02 51.16 Oesophageal pain | 6 0.06 51.22 Oesophagitis | 1 0.01 51.23 Oestrogen replacement therapy | 1 0.01 51.24 Off label use | 8 0.08 51.32 Oligomenorrhoea | 1 0.01 51.33 Onychoclasis | 1 0.01 51.34 Open angle glaucoma | 1 0.01 51.35 Oppositional defiant disorder | 9 0.09 51.44 Oral candidiasis | 1 0.01 51.45 Oral herpes | 1 0.01 51.46 Oropharyngeal cancer | 1 0.01 51.47 Oropharyngeal pain | 2 0.02 51.49 Orthostatic hypotension | 1 0.01 51.50 Osteitis deformans | 1 0.01 51.51 Osteoarthritis | 21 0.21 51.72 Osteogenesis imperfecta | 1 0.01 51.73 Osteomalacia | 3 0.03 51.76 Osteomyelitis | 1 0.01 51.77 Osteonecrosis | 1 0.01 51.78 Osteopenia | 17 0.17 51.95 Osteoporosis | 103 1.03 52.98 Osteoporosis postmenopausal | 8 0.08 53.06 Osteoporosis prophylaxis | 16 0.16 53.22 Osteosarcoma recurrent | 4 0.04 53.26 Ovarian cancer | 18 0.18 53.44 Ovarian cancer metastatic | 1 0.01 53.45 Ovarian cancer recurrent | 21 0.21 53.66 Ovarian cancer stage I | 2 0.02 53.68 Pain | 171 1.71 55.39 Pain in extremity | 20 0.20 55.59 Pain management | 3 0.03 55.62 Pancreas transplant | 1 0.01 55.63 Pancreatic carcinoma | 5 0.05 55.68 Pancreatic carcinoma metastatic | 2 0.02 55.70 Pancreatic neuroendocrine tumour | 10 0.10 55.80 Pancreatic neuroendocrine tumour meta.. | 1 0.01 55.81 Panic attack | 2 0.02 55.83 Paraesthesia | 1 0.01 55.84 Paranoia | 6 0.06 55.90 Parkinson's disease | 3 0.03 55.93 Parkinsonism | 2 0.02 55.95 Paroxysmal nocturnal haemoglobinuria | 17 0.17 56.12 Partial seizures | 4 0.04 56.16 Pemphigus | 2 0.02 56.18 Pericarditis | 1 0.01 56.19 Peripheral arterial occlusive disease | 2 0.02 56.21 Peripheral swelling | 4 0.04 56.25 Peritoneal dialysis | 4 0.04 56.29 Persistent depressive disorder | 1 0.01 56.30 Pharyngeal inflammation | 1 0.01 56.31 Phenylketonuria | 2 0.02 56.33 Pituitary-dependent Cushing's syndrome | 1 0.01 56.34 Plasma cell myeloma | 103 1.03 57.37 Platelet aggregation inhibition | 1 0.01 57.38 Platelet count decreased | 2 0.02 57.40 Platelet count increased | 1 0.01 57.41 Pleural effusion | 1 0.01 57.42 Pneumocystis jirovecii infection | 2 0.02 57.44 Pneumocystis test positive | 1 0.01 57.45 Pneumonia | 4 0.04 57.49 Pneumonia aspiration | 1 0.01 57.50 Pollakiuria | 4 0.04 57.54 Polychondritis | 3 0.03 57.57 Polycystic ovaries | 1 0.01 57.58 Polymyositis | 1 0.01 57.59 Polyneuropathy alcoholic | 1 0.01 57.60 Polyuria | 2 0.02 57.62 Portal vein thrombosis | 2 0.02 57.64 Post herpetic neuralgia | 1 0.01 57.65 Post laminectomy syndrome | 1 0.01 57.66 Post procedural infection | 2 0.02 57.68 Post transplant lymphoproliferative d.. | 22 0.22 57.90 Post-traumatic stress disorder | 25 0.25 58.15 Postoperative care | 1 0.01 58.16 Prader-Willi syndrome | 1 0.01 58.17 Premedication | 71 0.71 58.88 Premenstrual dysphoric disorder | 1 0.01 58.89 Procedural pain | 1 0.01 58.90 Product use in unapproved indication | 2 0.02 58.92 Product used for unknown indication | 2,171 21.71 80.63 Prolactin-producing pituitary tumour | 1 0.01 80.64 Prophylactic chemotherapy | 4 0.04 80.68 Prophylaxis | 198 1.98 82.66 Prophylaxis against gastrointestinal .. | 8 0.08 82.74 Prophylaxis against graft versus host.. | 23 0.23 82.97 Prophylaxis against transplant reject.. | 14 0.14 83.11 Prophylaxis of nausea and vomiting | 5 0.05 83.16 Prophylaxis of neural tube defect | 2 0.02 83.18 Prostate cancer | 15 0.15 83.33 Prostate cancer metastatic | 7 0.07 83.40 Prostate infection | 1 0.01 83.41 Prostatic disorder | 5 0.05 83.46 Prostatic specific antigen increased | 1 0.01 83.47 Prostatomegaly | 2 0.02 83.49 Pruritus | 10 0.10 83.59 Pseudomonal sepsis | 4 0.04 83.63 Pseudomonas infection | 2 0.02 83.65 Pseudoxanthoma elasticum | 1 0.01 83.66 Psoriasis | 174 1.74 85.40 Psoriatic arthropathy | 41 0.41 85.81 Psychotic behaviour | 1 0.01 85.82 Psychotic disorder | 53 0.53 86.35 Pulmonary arterial hypertension | 51 0.51 86.86 Pulmonary artery atresia | 1 0.01 86.87 Pulmonary embolism | 6 0.06 86.93 Pulmonary function test | 1 0.01 86.94 Pulmonary hypertension | 13 0.13 87.07 Pulmonary mycosis | 2 0.02 87.09 Pulmonary tuberculosis | 4 0.04 87.13 Pyelonephritis | 5 0.05 87.18 Pyelonephritis acute | 1 0.01 87.19 Pyrexia | 14 0.14 87.33 Quadriparesis | 1 0.01 87.34 Quadriplegia | 1 0.01 87.35 Rash | 5 0.05 87.40 Rash maculo-papular | 5 0.05 87.45 Rectal cancer | 9 0.09 87.54 Rectosigmoid cancer metastatic | 4 0.04 87.58 Red blood cell abnormality | 1 0.01 87.59 Reflux gastritis | 1 0.01 87.60 Refractory cytopenia with multilineag.. | 1 0.01 87.61 Refractory cytopenia with unilineage .. | 1 0.01 87.62 Relapsing-remitting multiple sclerosis | 16 0.16 87.78 Relaxation therapy | 1 0.01 87.79 Renal cancer | 5 0.05 87.84 Renal cancer metastatic | 1 0.01 87.85 Renal cell carcinoma | 5 0.05 87.90 Renal disorder | 2 0.02 87.92 Renal impairment | 1 0.01 87.93 Renal transplant | 18 0.18 88.11 Reperfusion injury | 1 0.01 88.12 Respiratory disorder | 8 0.08 88.20 Respiratory tract infection | 1 0.01 88.21 Restless legs syndrome | 6 0.06 88.27 Restlessness | 2 0.02 88.29 Retinal disorder | 2 0.02 88.31 Retinal vein occlusion | 2 0.02 88.33 Retinopathy congenital | 1 0.01 88.34 Retinopathy of prematurity | 1 0.01 88.35 Rheumatic disorder | 1 0.01 88.36 Rheumatoid arthritis | 279 2.79 91.15 Rheumatoid vasculitis | 1 0.01 91.16 Rhinitis | 1 0.01 91.17 Rhinitis allergic | 6 0.06 91.23 Rickets | 1 0.01 91.24 Right ventricular failure | 8 0.08 91.32 Routine health maintenance | 6 0.06 91.38 Sarcoma | 1 0.01 91.39 Schizoaffective disorder | 39 0.39 91.78 Schizophrenia | 145 1.45 93.23 Scleroderma | 1 0.01 93.24 Scoliosis | 2 0.02 93.26 Seasonal allergy | 4 0.04 93.30 Secondary progressive multiple sclero.. | 1 0.01 93.31 Sedation | 7 0.07 93.38 Sedative therapy | 2 0.02 93.40 Seizure | 27 0.27 93.67 Sepsis | 1 0.01 93.68 Septic shock | 1 0.01 93.69 Serous cystadenocarcinoma ovary | 4 0.04 93.73 Sexual dysfunction | 3 0.03 93.76 Sexually inappropriate behaviour | 4 0.04 93.80 Sinus disorder | 4 0.04 93.84 Sinusitis | 7 0.07 93.91 Skin burning sensation | 1 0.01 93.92 Skin infection | 1 0.01 93.93 Skin ulcer | 3 0.03 93.96 Sleep apnoea syndrome | 1 0.01 93.97 Sleep disorder | 42 0.42 94.39 Sleep disorder therapy | 5 0.05 94.44 Small intestine adenocarcinoma | 1 0.01 94.45 Smoking cessation therapy | 1 0.01 94.46 Somatic symptom disorder | 1 0.01 94.47 Somnolence | 2 0.02 94.49 Spinal column stenosis | 4 0.04 94.53 Spinal compression fracture | 3 0.03 94.56 Spinal osteoarthritis | 4 0.04 94.60 Squamous cell carcinoma | 3 0.03 94.63 Staphylococcal infection | 7 0.07 94.70 Status epilepticus | 2 0.02 94.72 Stem cell transplant | 15 0.15 94.87 Stent placement | 8 0.08 94.95 Stomatitis | 1 0.01 94.96 Streptococcal infection | 1 0.01 94.97 Stress | 11 0.11 95.08 Stress urinary incontinence | 1 0.01 95.09 Substance use disorder | 6 0.06 95.15 Supplementation therapy | 20 0.20 95.35 Supraventricular tachycardia | 2 0.02 95.37 Surgery | 1 0.01 95.38 Swelling | 1 0.01 95.39 Syncope | 1 0.01 95.40 Systemic lupus erythematosus | 15 0.15 95.55 Tachycardia | 5 0.05 95.60 Temporomandibular joint syndrome | 4 0.04 95.64 Testicular germ cell cancer metastatic | 6 0.06 95.70 Thalassaemia | 1 0.01 95.71 Thalassaemia beta | 1 0.01 95.72 Therapeutic procedure | 1 0.01 95.73 Throat irritation | 1 0.01 95.74 Thrombocytopenia | 3 0.03 95.77 Thrombolysis | 1 0.01 95.78 Thrombosis | 4 0.04 95.82 Thrombosis prophylaxis | 24 0.24 96.06 Thyroid cancer | 7 0.07 96.13 Thyroid cancer metastatic | 2 0.02 96.15 Thyroid disorder | 28 0.28 96.43 Thyroidectomy | 3 0.03 96.46 Tic | 5 0.05 96.51 Tobacco abuse | 1 0.01 96.52 Tooth abscess | 1 0.01 96.53 Tooth infection | 1 0.01 96.54 Toothache | 1 0.01 96.55 Tourette's disorder | 3 0.03 96.58 Toxicity to various agents | 1 0.01 96.59 Transfusion | 1 0.01 96.60 Transient ischaemic attack | 1 0.01 96.61 Transplant rejection | 1 0.01 96.62 Tremor | 3 0.03 96.65 Trigeminal neuralgia | 2 0.02 96.67 Tuberculosis | 5 0.05 96.72 Tuberous sclerosis | 1 0.01 96.73 Tumour pain | 1 0.01 96.74 Turner's syndrome | 1 0.01 96.75 Type 1 diabetes mellitus | 45 0.45 97.20 Type 2 diabetes mellitus | 137 1.37 98.57 Ulcer | 2 0.02 98.59 Unevaluable event | 1 0.01 98.60 Upper gastrointestinal haemorrhage | 1 0.01 98.61 Upper respiratory tract infection | 3 0.03 98.64 Upper respiratory tract inflammation | 6 0.06 98.70 Urge incontinence | 4 0.04 98.74 Urinary incontinence | 4 0.04 98.78 Urinary tract disorder | 3 0.03 98.81 Urinary tract infection | 10 0.10 98.91 Urinary tract obstruction | 1 0.01 98.92 Urticaria | 3 0.03 98.95 Uterine cancer | 5 0.05 99.00 Uterine contractions during pregnancy | 1 0.01 99.01 Uterine leiomyoma | 1 0.01 99.02 Vascular stent thrombosis | 1 0.01 99.03 Vasculitis | 1 0.01 99.04 Vasomotor rhinitis | 3 0.03 99.07 Venous thrombosis | 1 0.01 99.08 Ventricular extrasystoles | 1 0.01 99.09 Ventricular fibrillation | 1 0.01 99.10 Vertigo | 1 0.01 99.11 Viral infection | 1 0.01 99.12 Viral upper respiratory tract infection | 14 0.14 99.26 Visual impairment | 1 0.01 99.27 Vitamin B12 deficiency | 1 0.01 99.28 Vitamin C | 1 0.01 99.29 Vitamin C deficiency | 1 0.01 99.30 Vitamin D decreased | 2 0.02 99.32 Vitamin D deficiency | 6 0.06 99.38 Vitamin supplementation | 15 0.15 99.53 Vocal cord thickening | 5 0.05 99.58 Vomiting | 21 0.21 99.79 Vulvitis | 1 0.01 99.80 Vulvovaginal dryness | 2 0.02 99.82 Vulvovaginal mycotic infection | 1 0.01 99.83 Waldenstrom's macroglobulinaemia | 8 0.08 99.91 Weight control | 1 0.01 99.92 Weight decreased | 2 0.02 99.94 Wheezing | 2 0.02 99.96 Withdrawal syndrome | 1 0.01 99.97 Wound dehiscence | 2 0.02 99.99 Wound infection | 1 0.01 100.00 ----------------------------------------+----------------------------------- Total | 10,000 100.00 by Jean Roth , jroth@nber.org , 8 Feb 2018